All these aspects allow for a fine-tuned regulation of the actions that the melanocortin system controls, while simultaneously offering multiple ways to target and intervene the system for therapeutic purposes
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Attainment of secondary therapeutic goals with tirzepatide vs semaglutide Attainment of secondary therapeutic goals is presented in ESM Table 4
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The mass spectrometer was operated in the positive electrospray ionization (ESI) mode, and the MS/MS analysis was performed in the multiple reaction monitoring (MRM) mode, monitoring the transitions of m/z 162.0 103.0 for carnitine, m/z 147.1 88.1 for IS, respectively
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