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Handling & Safety This material should be handled only by qualified personnel using appropriate laboratory practices

Uncontrolled VEGF-A elevation has been associated with pathological angiogenesis, including tumor vascularization

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10.1123/ijsnem.11.4.451 111 OgasawaraR.SatoK.HigashidaK.NakazatoK.FujitaS

Oxygen-ozone (OO) therapy, an intervention that activates NRF2, increases SOD, catalase, and HO-1, while suppressing pro-inflammatory cytokines (IL-6, TNF-, IL-1) (33)