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The response to ER stress plays a pivotal role in MTX-induced apoptosis, where MTX primarily triggers ER stress via the PERK/CHOP pathway (Song et al., 2021)

Structure Sequence : H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Thr-Lys-Lys-Ser-Lys-Gln-Gly-Glu-Leu-Ala-Gln-Gly-Glu-Arg-Arg-Gln-Glu-Lys-Ala-Glu-Arg-Arg-Ser-Asp-Gly-Thr-Phe-Thr-Asn-Ser

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Rotating sites does not have to be a large change in location, a difference of inch is enough

Refrigeration is mandatory after reconstitution

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