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Use bacteriostatic water (0.9% benzyl alcohol) for multi-dose vials

Specificity of ligand-dependent androgen receptor stabilization: receptor domain interactions influence ligand dissociation and receptor stability

Retinol is significantly more likely to cause dryness, peeling, redness, tightness, and sensitivity, especially in the first two to four weeks of use

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Biosci Rep (2020) 40(1):BSR20191900

This engenders a short-term desensitization of the receptor or internalization leading to long-term downregulation due to receptor degradation with a rate k d which ranges from hours to days [20]