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For semaglutide, this means 0.25 mg weekly for the first four weeks

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It restores gut microbiota balance, strengthens intestinal barrier integrity, and suppresses LPS-induced hepatic inflammation

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These effects are linked to alterations in mitochondrial structure, such as changes in membrane phospholipid composition, viscosity, and the structure and function of lipid microdomains, which in turn affect membrane-bound signaling proteins (65, 66)