P., Lana, J
using the Broad Institutes Connectivity Map (cMap), a compendium of transcriptional responses to compounds, identified GHK as the most active of 1309 bioactive substances, uniquely capable of reversing the expression of 54 genes in a metastatic-prone signature for aggressive early stage mismatch-repair colorectal cancer
Glutathione regenerates other antioxidants after theyve done their job
Studies by Pickart and colleagues published in 2012-2018 showed that GHK-Cu treatment of cultured human fibroblasts altered expression of several thousand genes, with patterns indicating increased expression of genes involved in tissue repair, antioxidant responses, protein synthesis, and cellular rejuvenation
Retrieved 4 July 2015
Cell culture and bioluminescence analysis T cells, isolated from mice, were activated by CD3/CD28 Streptamer kit (#6-8920, iba, Goettingen, Germany) for 30 min and cultured in RPMI 1640 medium (#8123340, Gibco) containing 10% FBS (#A5669701,Gibco), 1% penicillin/streptomycin, 50 M -mercaptoethanol (Beyotime, Shanghai, China), 1 mM sodium pyruvate (Beyotime) and 100 U/mL interleukin-2 (#CK24, Novoprotein, Suzhou, Jiangsu, China)