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In summary, oral administration of iron chelators (especially DFP) provides a non-invasive and promising dosing route for treating brain iron accumulation, but it requires prolonged treatment to achieve effective concentrations, close safety monitoring due to chronic treatment at relatively large dose, and its efficacy might be constrained by peripheral iron binding and the need for sufficient BBB penetration

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Our cells need the energy to function at peak efficiency, but as we get older a lack of oxygen tells our cells its game over and eventually they shut down