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Insomnia was not among the most prominently reported adverse events in published phase 2 trial data, though gastrointestinal side effects such as nausea may indirectly disrupt sleep

Research shows that a notable proportion of weight lost during GLP-1 treatment can come from lean body mass rather than fat alone - depending on the medication, individual factors, and whether resistance training was maintained during treatment

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Li J, Somers VK, et al

This gives the appetite regulation system time to partially readapt at each level rather than experiencing the full rebound simultaneously

Some are bacteria-based: Pendulum, whose chief communications officer is the actor Halle Berry, sells a product called GLP-1 Probiotic, not to be confused with pills from a different company, Codeage, called GLP-1 Probiotic+