Always consult your physician before starting any new supplement, especially if you have existing health conditions, take medications, or are pregnant or nursing
The Bottom Line on Microdosing GLP-1 While the desire to minimize side effects and costs is understandable, microdosing GLP-1 medications carries significant risks without proven benefits
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Understanding how GLP-1 medications work in practice requires looking beyond the label
Despite the controversies about the expression of GLP-1R in vascular smooth muscle and endothelial cells, studies have shown that GLP-1RAs have anti-proliferative effects on these cells, and also reduced oxidative stress and increased the production of nitric oxide (NO) (137, 138)
[PubMed | ClinicalTrials.gov | DOI] Wadden TA, Chao AM, Engel S, et al