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Assessing an individuals long-term glycemic control and optimizing hyperglycemia management during hospitalization provides clinical benefit in guiding appropriate treatment planning

Recent metabolomics and animal studies showed that TMAO, an intestinal microbiota-dependent metabolite formed from dietary trimethylamine-containing nutrients such as phosphatidylcholine (PC), choline and carnitine, is linked to coronary artery disease pathogenesis, only in the presence of TMA/TMAO generation and intact gut microbiota 35,46

Hocking S, Samocha-Bonet D, Milner KL, Greenfield JR, Chisholm DJ

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In 2015, Abdel-Khalek et al

Some anti-diabetic medications are linked with an increased risk of weight gain or hypoglycemia which may reduce the efficacy of the intended anti-hyperglycemic effects of these therapies