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46(5): 7279 Chace DH, DiPerna JC, Mitchell BL, et al

These findings have not been replicated in human trials

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OSA Initiates Histone lactylation that drives PDE4B/FUS/AGT axis to pulmonary hypertension

The article describes several simultaneous processes beyond appetite suppression: improved insulin sensitivity, decreased hepatic glucose production, delayed nutrient absorption from slowed gastric emptying, and potential shifts in food preferences

The oral GLP-1 therapy is expected to broaden the obesity treatment market by offering a convenient pill alternative to injections, potentially increasing patient uptake