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Melanotan-1 (afamelanotide) has progressed through rigorous clinical development, received regulatory approval for EPP, and established a favorable safety profile across thousands of patient exposures

doi: 10.1016/j.intimp.2016.04.001 132 NeinastM.MurashigeD.AranyZ

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Fingeret, "There have been several very good papers in the past 30 years that show marijuana does reduce IOP, and in the level neighborhood of what an eye drop may do, but it's a very short half-life