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& Di Domenico, F

Uversky and Dunker, 2012a

Muscarine intoxications have caused death in humans (e.g., Nicholson and Korman 1997)

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Role of transcription factors in T cell exhaustion The expression of the TOX transcription factor is key to the process of T cell exhaustion, which is activated by the TCR pathway in response to prolonged antigenic stimulation and is induced by calmodulin phosphatase-mediated activation of NFAT [64, 65]

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