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A minimum cycle length of 3 months per medication is a reasonable floor, and 6 months per cycle allows for full dose titration and a meaningful period at therapeutic doses

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The main mechanism is to act on pancreatic -cells to stimulate their insulin secretion

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This is a major opportunity for further study for a few reasons: many women report that weight gain during menopause feels harder to manage and less responsive to their usual eating and exercise habits, and some anecdotally cite GLP-1s as the most effective intervention theyve tried