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Glucose-dependent insulinotropic polypeptide suppresses foam cell formation of macrophages through inhibition of the cyclin-dependent kinase 5CD36 pathway

doi: 10.15690/vramn.v69i9-10.1130 17 ClarkeG.StoneT

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Thus, tirzepatide has demonstrated significant efficacy in lowering HbA1c levels and body weight in individuals with T2D, often surpassing the results seen with other antidiabetic agents

This data underscores why replenishing glutathione precursors via NAC is a biologically plausible and vital strategy for addressing the cellular exhaustion seen in these conditions