As an independent investigator at Massachusetts General Hospital in the 1980s, Mojsovs expertise in the chemical synthesis of peptides led to her discovery of glucagon-like peptide 1 (GLP-1), a peptide of unknown function
doi:10.3390/mps7010017 Stone C, Harris DD, Broadwin M, et al
Am J Physiol Regul Integr Comp Physiol 292, R7785, doi: 10.1152/ajpregu.00832.2005 (2007)
Example After a Single 2 mg Dose Pharmacologists generally consider a drug eliminated after 5 half-lives, which lines up with the roughly 5-week clearance timeline
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80,83108 GLP-1 GLP-1 is produced by intestinal endocrine L cells, which promote insulin secretion, inhibit glucagon release, slow gastric emptying, reduce appetite, 109 and lose weight