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Durston S, Tottenham NT, Thomas KM, Davidson MC, Eigsti IM, Yang Y et al (2003)
Side Effects and Safety Comparison# BPC-157 Side Effects# Animal studies report no significant adverse effects at standard research doses
Our experience shows this is a common practice in research to reduce the number of administrations
(See the list of studies, linked here.) The EPIC trial's report concluded: "Chronic oral administration of pimobendan to dogs with echocardiographic and radiographic evidence of cardiomegaly [enlargement] secondary to MMVD, in the absence of concurrent cardiovascular medication, results in the prolongation of the preclinical period, and is safe and well tolerated." Note that, as big a step as the EPIC trial took for promoting pimobendan, its investigators still emphasized the necessity of both "echocardiographic and radiographic [x-ray] evidence" that the dog's heart is enlarged due to MVD
If youre getting procedures like microneedling, lasers, or chemical peels, follow your providers post-procedure instructions
These treatments also provide important metabolic and cardiovascular benefits, helping improve overall wellnessnot just appearance
