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R., & Battisti, A

Unlike the substrate-specific enzyme that hydrolyzes ThTP, synthesis of ThTP is currently known to be catalyzed only by the enzymes producing ATP through ADP phosphorylation

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PAGln was identified through untargeted metabolomic analysis in a large-scale clinical study to be increased in circulation and associated with CV-related disease and major adverse cardiovascular events (i.e., stroke, myocardial infarction, and death) 11

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Nature 424: 957961