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Compared with DPP-4 inhibitor users, those taking GLP-1RAs had a 13% lower risk of rheumatoid arthritis, 18% lower risk of gout and a modest reduction in osteoarthritis incidence over one year

This model emphasizes treating causes such as electrolyte imbalances, various types of anemia (including screening for testosterone deficiency related anemia), and vitamin and mineral deficiencies, as well as managing comorbidities like metabolic syndrome and glucose control

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2A), warranting clinical studies