It comes in five dose strengths : 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg
(average results) Wegovy (semaglutide) GLP-1 only In the STEP-1 study (68 weeks), average weight change was about: 14.9% with Wegovy 2.4% with placebo (dummy injection) What that looks like: If you start at 100 kg , 14.9% is about 15 kg lost on average
These natural approaches may provide metabolic benefits, but their effects are generally much smaller in magnitude compared to prescription GLP-1 receptor agonists like semaglutide
however, it piqued significant public and commercial interest in 2021 when the STEP-1 trial demonstrated up to 14% placebo-adjusted weight loss, leading to its approval as a weight loss drug, Wegovy
Endocrinology 159 , 665675 (2018)
Why Patients Look Beyond Ozempic Ozempic changed the conversation about weight loss