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Thus, throughout the manuscript (as with GLP-1 glucoregulatory function above), we aim to highlight studies that directly examine endogenous gut peptide action via receptor knockdown or antagonism

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In the ovaries, GLP-1: Reduces androgen production (less excess testosterone) Increases sex hormone-binding globulin Improves ovulation rates For people with PCOS, this can mean more regular cycles and better chances of ovulating

These larger, longer-duration studies will provide more definitive data on efficacy, durability of response, and the compounds broader metabolic profile