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In the multiple-dose trial, eligible subjects were healthy males, aged 1864 years, with a BMI of 20.029.9 kg/m 2 , and males with T2D diagnosed within the last 10 years, treated with diet and exercise and/or metformin, aged 1864 years, with a BMI of 20.037.0 kg/m 2 and glycosylated haemoglobin (HbA 1c ) of 6.59.0%

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The breakthrough is now called one of the most consequential health advances of the 21st century