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Processed Foods Fortified With Folic Acid These are not well metabolised by people with an MTHFR mutation: supermarket breads cereals commercial baked goods crackers processed grain foods energy drinks with synthetic B vitamins Refined Sugars and White Flours Increase inflammation and nutrient depletion

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Together, these interconnected mechanisms may constitute the molecular basis for the patients long-term clinical response

They increase satiety and reduce appetite and calorie intake

However, emerging reports of mood changes have raised concerns among potential users about whether these medications could trigger or worsen depression