However, as gallbladder disease is not an issue with sodium-glucose co-transporter-2 (SGLT-2) inhibitors (with similar weight loss) (89), and gallbladder events also occurred in GLP-1RA-treated patients well after weight reduction (90), other mechanisms are possibly in play
EHR=electronic health record
These de-identified data environments were specifically designed to enable data access and analysis without requiring Institutional Review Board oversight, approval, or exemption confirmation
That said, researchers may consult the above-cited trials for details of how it has been administered in the past
It also provides a safer way for patients who are cautious about medications to explore the health benefits of GLP-1 receptor agonists without committing to a full-dose program from the start
At week 13, significant, dose-dependent reductions in HbA 1c (the primary endpoint) were reported [10]