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A year past expiration, your 5mg dose might deliver the equivalent of 4.4mg or less

They might need shots more often

Research shows that around 50 percent to 60 percent of ingested vitamin B12 is usually absorbed when enough intrinsic factor is present in relation to B12, but absorption decreases drastically when this ratio changes

Multivitamins normally contain only small amounts of B12, which might not be enough for vegans

By adjusting B12 doses for each patient, doctors can make treatments better and improve life quality

Each works on a different lever, which is exactly why a provider may use one, another, or a combination depending on your goals