But that used a modified compound, professional penetration enhancers, and rat skin
Semaglutide, as a pure GLP-1 agonist, causes GI side effects primarily through delayed gastric emptying
( Epub 2019 Jul 11 PMID: 31296642 ) Ornelas C, Caiado J, Lopes A, Pereira Dos Santos MC, Pereira-Barbosa M (2018) Anaphylaxis to long-acting release exenatide
Since these drugs are relatively new and we are still learning about all their effects, surgeons and anesthesiologists have not had guidelines for management of these medications around surgery until recently
Tirzepatide formulations often include glycine and B12 or niacinamide as supporting compounds
If you are transitioning from another GLP-1 medication, the timeline may differ slightly