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Hormonal Regulation Stabilising insulin and oestrogen levels may help with: Less uterine muscle hyperstimulation Fewer prostaglandin surges (compounds linked to cramping) Could Mounjaro Make Cramps Worse

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Preclinical work cited in the post suggests GLP-1 agonism may reduce production of the pro-inflammatory cytokines TNF-alpha and IL-6, which are already established therapeutic targets in RA

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