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Programmed cell death may also be mediated by the effect of elevated ROS on sphingomyelinase, which generates ceramide from sphingomyelin and binds to death receptors on the cell membrane of cancer cells

Whereas pharmacotherapeutic and other interventions have steadily improved the prognosis of other types of cardiovascular disease (CVD) and associated sequelae, HF remains associated with more pronounced morbidity and mortality, constituting one of the most pronounced unmet needs in cardiovascular medicine (Shah et al., 2020)

Erythrocytes are constantly exposed to OS due to the presence of ROS, which are countered by the endogenous antioxidant system

Lund, J

Diarrhea: This side effect is like a sudden rainstorm that can dampen any Hollywood premiere, but patients can manage it by staying hydrated and eating a balanced diet that's high in fiber

Moiz V, Andreu A, Rodrguez L, Flores L, Ibarzabal A, Lacy A, et al