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In line with the preclinical evidence, a number of clinical observations in NS and rotating shift workers across various populations and settings consistently suggest that NSW is associated with elevated oxidative stress and DNA damage, along with alterations in antioxidant defense systems 64

UPR is a highly conserved pathway that monitors endoplasmic reticulum (ER) proteostasis, allowing cells to manage ER stress (Moncan et al., 2021)

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Santidrian, A

25 l of serum or tissue homogenate sample was added to 1.5 ml of working solution and incubated at 37 C for 10 min, then the optical absorption was recorded at a wavelength of 593

Glucocorticoid regulation of inflammation and its functional correlates: from HPA axis to glucocorticoid receptor dysfunction