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Low levels have been linked to several issues, including a decline in brain function and a possible link to depression

2 3 Pickart L, Margolina A

Instead of antibody recognition, it identifies compounds by their mass-to-charge ratio and fragmentation patterns

Long-term use of metformin, proton pump inhibitors or H2 blockers , which can reduce B12 absorption over years

What made it even more effective is that it did not affect the activity of any other enzymes in the metabolic cycles which reduced the risks of any potential side-effects

Allow the solution to incubate for 15-30 minutes to facilitate complete dissolution