is semaglutide safe to use Compounded Safety: What You Should Know Semaglutide Associated With Reduced Risk

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20% of patients discontinued semaglutide due to gastrointestinal side effects

They include: feeling or being sick diarrhoea constipation These side effects are more likely to occur when the treatment first starts or when the dose increases

Wegovy should not be used by people with a personal or family history of medullary thyroid carcinoma, MEN 2, or serious allergy to semaglutide, and medical advice is required before use in pregnancy, breastfeeding, diabetes, kidney problems, pancreas problems, or before surgery

NCSL Resources on GLP-1 Drugs Prescription Drug Legislation Database Prescription Drug Policy Resource Center The Debate Over Weight-Loss Drugs Diabetes State Mandates and Insulin Copayment Caps The average annual list price of GLP-1s is $12,000 and, according to a Peterson-KFF tracker, most large employer health plans restrict coverage for weight loss

Semaglutide is primarily broken down through protein degradation rather than kidney or liver metabolism, but your provider will consider your specific situation