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Treatment plans are tailored to each patient and supported by an experienced medical support team that remains available throughout your care

Microbial tryptophan metabolites regulate gut barrier function via the Aryl hydrocarbon receptor

In the context of drugs being tested for the control of hyperphagia in PWS, the association of tesofensine (a presynaptic absorption inhibitor of noradrenaline, dopamine and serotonin) and metoprolol (a selective beta-blocker) is currently in phase 2b of experimentation and has already shown promising results, in fact, in a phase 2a study involving 18 patients with PWS, this association reduced body weight, improved BMI and reduced hyperphagia to very low levels

10.3390/pharmaceutics15082042 106 KolesnikI.TverdokhlebovaT.DanilenkoN.PlotnikovE.KulbakinD.ZheravinA.et al (2021)

Ulmasov T, Ohmiya A, Hagen G, Guilfoyle T 1995 The soybean GH2/4 gene that encodes a glutathione S-transferase has a promoter that is activated by a wide range of chemical agents

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