Similar to global findings, the majority of the participants in the studies in this review were females with obesity, and most did not have diabetes
Q: How long would I need to be on a GLP-1 medication before it could cause cancer
quadriceps, glutes, etc) Progressive loading where possible Protein intake A reasonable evidence-informed target for preserving muscle during weight loss is: 1.21.6 grams of protein per kilogram of body weight per day Many patients on GLP-1 medications unintentionally under-eat protein because appetite is reduced
In December 2025, Eli Lilly announced topline results from the phase-3 TRIUMPH-4 clinical trial evaluating the safety and efficacy of retatrutide in adults with obesity or overweight and knee osteoarthritis, and without diabetes, as an adjunct to healthy diet and physical activity
2020;105:e154960
Carvallo A, Silva C, Gastaminza G, et al