The Fast Facts As of January 2026, Wegovy (semaglutide) is now available in an oral pill form
Please talk with your doctor, dietician, or other certified health professionals when seeking advice about your own weight loss or weight maintenance plan
Interleukin-2 (IL-2) Interleukin-2 (IL-2) is another type of immunotherapy that helps strengthen the immune system so it can better fight cancer
(A-C) Dissected third larval stage (L3) gonads grown at 15C before sperm differentiation, stained with -FLAG (magenta) and DAPI (cyan)
A head-to-head clinical trial (SURMOUNT-5) published in The New England Journal of Medicine in 2025 also demonstrated the superiority of tirzepatide over semaglutide
Even though the pharmaceutical industry appears to have largely withdrawn its interest in pursuing the H3R as an anti-obesity target (189), work endures to optimize H3R ligands and explore their potential to influence food intake and body weight, and H3R antagonists/inverse agonists continue to be proposed for the treatment of obesity (190, 191)
