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So the need of the hour was an indepth study as a double blind placebo controlled clinical trial to study the effect of high dose thiamine therapy on biochemical profile and activities of thiamine dependant enzymes in type 2 diabetic patients in our multiracial population in Pakistan

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Additionally, in the US and Canada, white flour has been enriched with riboflavin since the 1940s

The drug was also linked with significant increases in retinal/vitreous detachment, retinal/vitreous hemorrhage and retinal tears