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Studies using the Broad Institute's Connectivity Map found that GHK significantly increased expression of DNA repair genes with 47 genes stimulated and 5 genes suppressed, providing a mechanism for cellular recovery from various forms of damage

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These mechanisms capture iron/haem molecules that are free in solution or complexed with host proteins and shuttle the iron/haem moiety across the cell wall and both bacterial membranes in a series of protein-ligand interactions ( Figure 1 ) (Rodrguez-Arce et al., 2019)