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Description

Selective NNMT inhibitors (including 5-Amino-1MQ) lower 1-MNA, increase NAD and SAM, suppress adipocyte lipogenesis, and reverse HFD-induced obesity in mice [1]

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at high doses , it can become neurotoxic or act as a pro-oxidant

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S2CID 7282489

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Preliminary findings from these studies suggest a tolerable oral dosage of approximately 100mg/kg in mice [1]

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