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Many toxicologists would recommend repeating the measurements of alanine aminotransferase and acetaminophen concentrations as the patient approaches the end of the 16-hour infusion period and continuing treatment if the alanine aminotransferase concentration is elevated or if the acetaminophen concentration is measurable

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However, as human erythrocytes are nucleus- and organelle-free cells, the effects of erythrocytic ceramides should be restricted to the plasma membrane and plasma membrane-associated proteins

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