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Nucleic Acids Res 49 , 285305 (2020)

If symptoms arise, you do not know which compound caused the issue

This stepwise titration lets you monitor tolerance while gradually reaching the effective dosing levels observed in preclinical research [1] [4]

In contrast, certain other GLP-1 receptor agonists (liraglutide, semaglutide, dulaglutide) have demonstrated cardiovascular benefits in their respective outcomes trials