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Appetite suppression may begin within days, but full weight-loss effects develop over weeks to months

Possible side effects of phentermine/topiramate ER (Qsymia) Qsymias side effects include headache, nausea, and brain fog, which happen less commonly

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These side effects are typically modest and resolve within a few weeks

Microdosing starts at doses below the lowest commercially available starting dose and is titrated slowly to achieve neuromodulatory and metabolic effects without the full appetite suppression or side effects of standard dosing