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To examine the requirement of the peptide hormone N-terminus for receptor activation, we fused full length or N-terminally truncated GLP-1 or EX4 peptide via a 15 amino acid linker (five copies of Gly-Ser-Ala [5xGSA]) to the N-terminus of GLP-1R (Figure 1b)

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Consent for publication Written informed consent was obtained from the patient for publication of this case report and any accompanying images

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initially disparaged the compounds for treating diabetes and obesity, instead insisting that Americans eat better