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Delaying treatment increases the risk of severe, irreversible damage to the lips, face, and even systemic health

Science 376 , 410416 (2022)

Methionine synthase is an important enzyme that uses methylfolate, a product made by the MTHFR enzyme and methylcobalamin, a form of vitamin B12, to do its job.1 It has two main jobs: First, it converts homocysteine, a potentially harmful amino acid, into methionine, which is essential for supporting the building of proteins and cell repair

Human Plasma ATP Concentration

The increased oxidative load disrupts the bodys intrinsic antioxidant defense systems, such as manganese superoxide dismutase (MnSOD) and glutathione peroxidase (GPx), leading to lipid peroxidation, DNA damage, and activation of pro-apoptotic pathways, such as p53 and BAX 5,7