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Exposure to HO resulted in a + 64 Da mass shift, consistent with overoxidation of Cys10 to sulfinic acid, together with oxidation of two methionine residues in the sequence

In light of the partly opposing effects of GIP on insulin secretion and on fat deposition, we have doubts whether either agonists or antagonists at the GIP receptor will play a therapeutic role [11]

Starting with a slightly lower dose for the first week can minimize any adjustment period while still providing benefits

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