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Through dual pathway activation, tirzepatide improves glycemic control and induces substantial weight loss across clinical trials (15)

The twice-daily structure requires strict adherence to 12-hour intervals

Sleep deprivation increases inflammatory markers and impairs immune regulation

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Am Fam Physician (2017) 95(1):403

HN was supported by a Sunstar Foundation postdoctoral fellowship and a Japan Society for the Promotion of Science (JSPS) Overseas Research Fellowship