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GLP-1 medications are prescription treatments and are not suitable for everyone

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Seek urgent medical advice if diarrhoea persists beyond seven days, blood or mucus appears in the stool, or signs of dehydration, pancreatitis, or gallbladder disease develop

The SH2 domain mediates tyrosine phosphorylation, primarily by JAK2, and subsequent homo- or heterodimerization of STAT5 proteins

This information could also guide decisions on whether monotherapy, combination therapy or bariatric surgery is the most appropriate course of action