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By re-expressing GSTP1, increased detoxification, and reduced levels of oxidative stress could potentially contribute to reduced prostate cancer progression and even to an abrogation on evolution toward invasive and metastatic disease

Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes

The result showed that GS-4997 greatly decreased LDs number compared to GSTM2 knockdown cells (Fig

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