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In clinical trials of Wegovy as an adjunct to lifestyle modification, participants lost an average of 15 percent of their body weight with more than half the people treated with Wegovy losing more than 15 percent of their starting weight - up to five times the average weight loss seen with traditional diet and exercise plans

Patients should understand that expected weight loss varies by medication (approximately 5-10% with liraglutide, 10-15% with semaglutide, and potentially higher with tirzepatide), though responses in post-bariatric patients may differ from those in primary obesity treatment

Quality of evidence: I-A, Strength of recommendation: 1 Panel level of agreement: In total agreement 96%, in partial agreement 4% Lactulose is the most widely used nonabsorbable disaccharide for the treatment of HE

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76 489497 10.1002/jmv.20388 [DOI] [PubMed] [Google Scholar] Anathy V., Roberson E

After 3-5 days, gradually introduce insoluble fiber like whole grains, leafy greens, and vegetables