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You should only ever take methylene blue under the care of a doctor

It focuses on hyperpigmentation, dark spots, and uneven skin tone to help create a smooth, more even look

NICE NG28 emphasises that HbA1c targets should be individualised, taking into account patient preferences, comorbidities, and risk of hypoglycaemia, rather than applying a single universal threshold

Patients should seek immediate medical attention for severe abdominal pain, persistent vomiting, visual changes, or suicidal thoughts

It is unclear why directionality would vary between studies, although we note these studies were performed in specific disease contexts, and are in substantially smaller samples

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