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However, ARS induced ROS-dependent apoptosis in HeLa and A549 cell lines but ROS-independent apoptosis in HepG2 cells

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We have identified 2 meta-analyses assessing the combination therapy in CVOTs (Table 1)

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Common Topamax side effects include: Nausea and diarrhea Dizziness, drowsiness, and trouble concentrating Numbness or tingling in the arms or legs Less common side effects that may be more severe include: Skin reactions, no matter how mild Vision problems, such as blurred vision Signs of kidney stones Symptoms of dehydration Allergic reaction Drinking alcohol with Topamax can lead to serious side effects like dehydration