This product is classified as an investigational research compound and is not authorized for therapeutic, diagnostic, or consumer use in Canada when supplied in research format
Hepler C, Shan B, Zhang QB, Henry GH, Sheo ML, Vishvanath L, Ghaben AL, Mobley AB, Strand D, Hon GC, et al
[DOI] [PubMed] [Google Scholar] Ng K.-M., Chau S.-L., Tang H.-W., Wei X.-G., Lau K.-C., Ye F., Ng A
6.1 Diabetes Type I diabetes, Type II DM, and gestational diabetes are characterized by hyperglycemia, dyslipidemia, and insulin resistance, which increase oxidative stress and activate the protein kinase C (PKC) as well as the receptor for advanced product glycation (AGE) and low levels of antioxidants and GPx in diabetic patients
Safety is uncertain because most patches are not well-studied in humans
and in combination with basal insulin with or without metformin (SURPASS-5)